16479 Dallas Parkway, Suite 320, Addison, Texas 75001
Office Hours: Monday-Thursday 9am-7pm | Friday 9am–1pm

Call (469) 484-4260


Spravato® is an FDA-approved breakthrough treatment for treatment resistant major depressive disorder (TRD) in adults. It is an intranasal medicine, prescribed along with an oral antidepressant.


Who can benefit from Spravato?

If you’ve struggled with depression and have tried two or more antidepressants in your current episode without adequate relief, talk with your current doctor or schedule an evaluation with us to see if Spravato may benefit you.

Also known as intranasal esketamine, Spravato is FDA-approved and typically covered by insurance, making it affordable for individuals with insurance. Spravato may only be administered by a trained provider in a certified office environment where patients can be monitored.

The Dallas Center for Advanced Depression Treatments (CADT) is a certified treatment center and Dr. Bennett was one of the first psychiatrists to prescribe it in the Dallas area following its FDA approval in 2019.

The Dallas CADT has quickly become the largest Spravato treatment center in North Texas and has been chosen as one of only four national training centers for Spravato-certified providers. We believe our deep experience with this drug is important in obtaining the best outcomes for our patients.


How does Spravato work?

Spravato is thought to work as a treatment for depression by acting as an antagonist to the NMDA glutamate receptor, a mechanism similar to that of ketamine.

By blocking the NMDA receptor, esketamine is hypothesized to lead to the formation of new neural connections and the restoration of neural plasticity. Patients often report symptom improvement within days instead of weeks as with traditional oral antidepressants.

Before you can be prescribed Spravato, your first visit will be a consultation with one of our providers to discuss your medical history and any other treatments you’ve tried for depression. There are also certain medical conditions that might mean you shouldn’t use Spravato, so it’s important to be aware of your medical history.

All patients are required to register with the Spravato Risk Evaluation and Mitigation Strategy (REMS) program, and most patients will require a prior authorization from their insurance company prior to initiating treatment. If it is determined that Spravato is a good treatment option for you, our staff will initiate the registration and request the insurance authorization. Generally this approval is received within 3-10 business days, but different insurance companies vary.


What happens during Spravato treatment?

Each treatment session lasts two hours, during which patients are monitored in a private, comfortable setting.

Like all medicines, Spravato can have side effects. Some patients report feeling a bit disconnected from themselves, dizzy, or sleepy. However, 99% of all side effects resolve before being discharged from the office after treatment. Patients are not allowed to drive after treatment and must be picked up by a friend, family member, or ride share service.

The initial phase of treatment, or induction, consists of twice-weekly visits for four weeks.

If a patient has shown satisfactory response to treatment after these eight treatments, they most often are treated with a maintenance course of once-weekly treatment for four weeks and then either once weekly or every two weeks depending on individual response.

Spravato has been shown to be safe and effective at preventing relapse with data now surpassing five years and over 800,000 individual treatments.


Progressive Therapies for Difficult to Treat Mental Illness

Depression is the leading cause of disability worldwide, with about 9.5 percent of adults in the United States experiencing it annually. When individuals suffer from depression that remains unresponsive to conventional treatments, novel therapies often can improve outcomes.

Spravato® nasal spray

Spravato® is an FDA-approved nasal spray to treat adults with major depressive disorder that have failed to improve after the use of two oral antidepressants.

Read more
BrainsWay Deep TMS™

BrainsWay Deep TMS™ is a form of transcranial magnetic stimulation, a non-medication depression therapy.

Read more
Intranasal Ketamine

Intranasal ketamine is a less invasive, affordable alternative to IV ketamine treatment.

Read more
Abilify Long-Acting Injectables

Abilify Maintena and Asimtufii are maintenance treatments for patients with bipolar 1 disorder.

Read more
General Psychiatry

Traditional psychiatric care for mental health conditions, including depression, bipolar, anxiety, ADHD, and thought disorders.

Read more
Testosterone Therapy

Symptoms of low testosterone are often confused with depressive illnesses and can be managed with medication.

Read more
Genetic Testing

Genomind offers non-invasive genetic testing for personalized psychiatric medication effectiveness.

Read more

Take the first step towards healing
and well-being

We understand that dealing with depression can be challenging and complicated, but you are not alone. Contact us today and let's work together to navigate your journey towards a healthier, happier life.

Preston Hollow Psychiatry Group © 2024. All Rights Reserved.

Schedule An Appointment Schedule An Appointment